Kidney Biopsy Un-masquerading Plasma Cell Leukemia Diagnosed as Acute Myeloid Leukemia: An Unusual Clinical Experience

Plasma cell leukemia (PCL) is a rare aggressive variant of plasma myeloma. The differential diagnosis PCL includes multiple myeloma (MM), other leukemias, and lymphomas with abnormal cells circulating in the peripheral blood. In addition, infectious or autoimmune diseases can cause reactive polyclonal plasmacytosis, which could confuse us occasionally. Sometimes, blastoid morphology confusion diagnosis, immunohistochemistry needed to differentiate from forms leukemias lymphomas. Here, we present case diagnosed as acute myeloid (AML) kidney biopsy establishing correct diagnosis.